Hemoglobin Variant Analysis (HBe lectrophoresis)
The Hemoglobin HPLC / Electrophoresis test is a blood test used to check for normal and abnormal types of hemoglobin in the blood. This test helps detect and monitor blood disorders like thalassemia and sickle cell disease.
Sample Required
🩸 Blood
This test is for
👤 Male, Female
Earliest reports in
⏱ 48 hours
Contains
🧪 8 tests
- Detect hemoglobin variants
- Diagnose thalassemia (alpha & beta)
- Diagnose sickle cell disease and trait
- Screen carriers of hemoglobinopathies
- Monitor hemoglobin levels after transfusion
- Evaluate unexplained anemia
- Detect fetal hemoglobin rise
- Support family screening
Method Name
🧬 HPLC (High Performance Liquid Chromatography), Capillary Electrophoresis (depending on lab)
Preparations Required
- ✓ Record the date of birth
- ✓ sex
- ✓ race and religion on the test request form for sample collection.
Know more about this test
The Hemoglobin HPLC / Electrophoresis test provides a detailed breakdown of hemoglobin types in the blood. Doctors recommend this test if they suspect anemia... The Hemoglobin HPLC / Electrophoresis test provides a detailed breakdown of hemoglobin types in the blood. Doctors recommend this test if they suspect anemia, thalassemia, sickle cell disease, or other hemoglobin disorders. No fasting is required. Recent blood transfusions may affect results, so informing the doctor is important. Results differ based on age, gender, health condition, and laboratory technique. Doctors interpret the results alongside CBC, family history, and clinical symptoms to decide treatment or further testing. see more
Understanding Hemoglobin Variant Analysis
What is Hemoglobin HPLC / Electrophoresis?
The Hemoglobin HPLC / Electrophoresis test is a blood test used to check for normal and abnormal types of hemoglobin in the blood. This test helps ... The Hemoglobin HPLC / Electrophoresis test is a blood test used to check for normal and abnormal types of hemoglobin in the blood. This test helps detect and monitor blood disorders like thalassemia and sickle cell disease. Hemoglobin (Hb) is a protein in red blood cells that carries oxygen to the body’s organs and tissues. The Hemoglobin HPLC / Electrophoresis test gives a detailed report of the different types of hemoglobin, such as HbA (normal), HbF (fetal hemoglobin), and other abnormal types like HbD. This test is useful in spotting disorders that are linked to abnormal hemoglobin. It also helps doctors check how well treatment is working in people who are receiving blood transfusions or medication. The doctor may advise this test if a blood disorder like thalassemia or sickle cell disease is suspected. Common signs include dizziness, weakness, pale skin, cold hands and feet, frequent infections, shortness of breath, fast heartbeat, or weight loss. The test may also be suggested if there is a family history of blood disorders, unexplained anemia, or abnormal results in other blood tests. Fasting is not required for this test. Eat and drink as per the daily routine. Inform the doctor of any recent blood transfusion, as it may affect the test results. The normal ranges of results can vary based on age, gender, health history, and the lab that does the test. The doctor will explain the results by looking at other tests like CBC, family history, and overall health. Based on the findings, the doctor will decide if any treatment or medication is needed. Test result ranges are approximate and vary depending on age, gender, health history, and methodology used by the laboratories. Talk to the doctor about specific test results. The doctor may consider several additional factors while interpreting the significance of abnormal hemoglobin, including family history, the results of CBC, and more. Based on the test results, the doctor decides whether or not medication will be required to manage the condition and formulate an overall treatment plan. read more
What is Hemoglobin HPLC / Electrophoresis used for?
The Hemoglobin HPLC / Electrophoresis test can be done: Check the types of hemoglobin in blood, both normal and abnormal. Screen for inherited... The Hemoglobin HPLC / Electrophoresis test can be done: Check the types of hemoglobin in blood, both normal and abnormal. Screen for inherited blood disorders like thalassemia and sickle cell disease. Track how well treatment is working in people with blood disorders. Monitor people who have a family history of blood disorders. Follow up on unusual results in other blood tests related to red blood cells. read more
- HbA (Adult Hemoglobin)
- HbA2
- HbF (Fetal Hemoglobin)
- HbS (Sickle Hemoglobin)
- HbE
- HbD
- HbC
- Hb Variant Detection
- Hb Quantification %
- Retention Time Analysis
What Each Test Measures

Home Collection
STEP 1
Easy Online Booking
Select test, time, and address online.
STEP 2
Live Tracking
Track Phlebotomist In Real Time
STEP 3
Safe Collection
Safe Sample Collection With Safety Protocols
STEP 4
Lab Testing
Sample Sent To Certified Lab For Testing
STEP 5
Quick Reports
Get Reports By Email Or WhatsApp With Free Doctor Consultation
Frequently Asked Questions
You need this test if your doctor suspects you may have a blood disorder such as thalassemia or sickle cell disease, or if someone in your family has such a disorder.
A blood sample is taken from your arm and sent to the laboratory. The machine separates different types of hemoglobin and compares them with standard values to give accurate results.
This test is very safe. You may feel slight pain or develop a small bruise where the needle was inserted, but serious complications like infection or heavy bleeding are rare.
Diet, age, gender, smoking habits, altitude (place where you live), certain medicines, and some illnesses may influence the results.
Yes. If there is a family history of hemoglobin disorders, this test can help screen other family members and assist in family planning.
Yes, it can be part of newborn screening to detect blood disorders early and start prompt treatment if needed.
Hemoglobinopathy refers to inherited disorders in which the body produces abnormal hemoglobin. These conditions are passed from parents to children.
Common types include: Hemoglobin C disease Hemoglobin S-C disease Sickle cell anemia Thalassemia
Complications may include: Infections, iron overload, bone deformities, enlarged spleen, delayed growth, and heart problems.
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FAQs
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What are CureBay Health Packages?
CureBay Health Packages are a combination of essential diagnostic tests and preventive checkups, designed to monitor overall health and detect potential issues early.
How can I book a package?
You can easily book through CureBay’s website, mobile app, or helpline. Once booked, you’ll receive confirmation and a phlebotomist will be scheduled for home sample collection.
Can I book tests for my family members?
That depends on the supplement and your personal health goals. The results are visible depending on your consistency. Remember to be consistent to feel a noticeable difference.
How will I get my reports?
Reports are delivered digitally within the mentioned TAT (Turnaround Time) via Email, WhatsApp, and CureBay’s platform.
Are doctor consultations included in the packages?
Many packages include complimentary doctor consultations to help you understand your test results and guide next steps for better care.
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Hemoglobin Variant Analysis (HBe lectrophoresis)
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Home Sample Collection
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First & Accurate Report
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