Double Marker with Graph

The Double Marker Test- First Trimester also known as a dual marker test, assesses specific biomarkers in a pregnant woman’s blood. It is done duri... The Double Marker Test- First Trimester also known as a dual marker test, assesses specific biomarkers in a pregnant woman’s blood. It is done during the first trimester of pregnancy, usually between 11-13 weeks. This test provides information about the risk of certain birth defects such as Down syndrome (Trisomy 21), Edward syndrome (Trisomy 18), and Patau syndrome (Trisomy 13) in the developing fetus. Prenatal care is necessary to ensure a healthy pregnancy and successful childbirth. Early prenatal screenings identify potential health concerns and guide medical interventions when necessary. The Double Marker Test- First Trimester is essential for early prenatal assessment. It offers invaluable insights into the developing fetus's chromosomal health. The test primarily measures two important biomarkers in the mother’s blood—human chorionic gonadotropin (hCG) and pregnancy-associated plasma protein A (PAPP-A). Both the markers are produced by the fetus and the placenta. The test also checks if the baby might be at risk for certain genetic problems, especially Down syndrome and Edwards syndrome. These conditions happen when there is an extra copy of chromosome 21 or 18, respectively. They can affect a baby's physical and intellectual development. However, a Double Marker Test-First Trimester is a screening test, not a diagnostic one. It does not determine whether the baby has abnormalities. Instead, it tells whether the unborn baby is at risk of developing certain abnormalities. The test results are reported as a risk score or probability of the fetus having a chromosomal abnormality. Test results within the expected range suggest a lower risk of chromosomal abnormalities. On the contrary, high levels may indicate a higher risk of chromosomal abnormalities and prompt further testing. Furthermore, a positive screen result (high risk) does not confirm a genetic problem. It may suggest that further testing may be needed to check the baby's health more closely. On the other hand, a negative screen result (low risk) does not guarantee the absence of fetal defects. In combined risk assessment, the NT scan (a type of ultrasound) is also used to check for conditions like Down syndrome and Patau syndrome. This, along with the mother’s details—such as age, weight, smoking, diabetes, or IVF pregnancy—is included in the overall risk calculation. However, this test does not check for neural tube defects. No fasting is required for a Double Marker Test-First Trimester. Let the doctor know about any medical conditions, allergies, or medicines being taken, as some medicines may affect the test results and might need to be stopped before getting tested. Talk to the doctor about the specific test results. The accuracy of the results is subjective to the information provided in the screening form. This information is mandatory for combined risk assessment. read more

The Double Marker Test- First Trimester is done: For the early risk assessment of Down, Patau and Edward syndromes in developing fetuses. In pr... The Double Marker Test- First Trimester is done: For the early risk assessment of Down, Patau and Edward syndromes in developing fetuses. In pregnant women above 35 years of age and those with a family history of birth defects and a history of insulin-dependent type 1 diabetes. read more